So many choices,.. so little time,...
S&W 686, 3 or 4" .357. or Model 460V, fires 45LC, 454 Casull, or the .460. slightly bigger at 5".
Or the Model 329 .44, although the 2.5" barrel is stout by any standard.
Ruger wheel's are always a winner. SP's, new Redhawk in .45LC, SA, would go to the Vaquero.
And, as always, there's a 1911,.. Sorry,... wrong thread.