In US v. Miller, the court found that the defendant had not shown that a shotgun with a barrel length below 18" constituted a "Militia Weapon". The court did not recognize that the NFA of 1934 also taxed machineguns, nor did the court recognize that the tax imposed exceeded the value of most arms on which it was imposed, which therefore violated the Bailey v. Drexel furniture decision which requires taxes be only for revenue generation and not back-door prohibition. The failure to bring these issues before the court is what caused the court to find for the government. The defendant did not appear, nor did anyone else appear for the defendant, had anyone appeared to bring these issues to light the NFA would have gone down. You will note that the NRA SUPPORTED the NFA and had no interest in acting in the matter.
IF the court finds for the Individual rights understanding, I expect that the vast majority of anti-self defense to be challenged in court. However, what I also expect is that the court WILL find for individuals, whereupon the congress will invoke Article III section 2 and exempt second amendment cases from supreme court review, and proceed to pass whatever they want. Once this happens the 2nd amendment will be a dead letter, and America will cease to exist in under 24 months as armed insurrection begins (probably of the "Unintended Consequences" variety). Of course I have been accused of pessimism before.