I only have a fuzzy understanding of "Bullet Energy" I just work on the principle's that
1- Bigger holes bleed faster
2- If one is good 14 are better\
3 - Placement rules them both
The way I understand it all the damage a bullet does besides the hole, is caused by the transfer of the (Bullet weight and velocity ) into the surrounding tissue This energy dump is aided by expanding bullets since they present a larger frontal area creating a greater amount of drag. (and a bigger hole )
My conclusion comes simply from thinking about it not any math, but it seems to me that while you need enough penetration to reach vital organs, but if your bullet goes clean through then you have wasted that energy and would be better served by a heavier bullet on the same powder charge.