Just so you know the difference between standard primers and magnum primers is; The cup on a magnum is either thicker or of a stronger/harder brass compound (this is to resist peirced/ruptured primers with the higher pressures found in magnum loads) and magnums have a slightly larger amount of priming compound or a hotter priming compound (to more efficiently ignite the slower powders commonly found in magnum loads).
With that being said the actual effect on your load performance, groupings and safety between the two is dependent on alot of factors that can get confusing and complicated. So as a rule of thumb if your load is normally with a standard primer and you switch to a magnum:
If it is at or close to max charge reduce the load 10% to caution on the side of safety.
If it is a light or medium range load than there is no safety concern. Try it and you might find there is no difference in groups or point of impact.
A definent performance problem with going to a magnum primer from a standard one is in a "tuned" revolver. If you have a lightened mainspring (or competition spring kit). The hammer energy will be to little to overcome the harder/thicker cup on the magnum primer thus a whole lot of failure to fires! Hope this helps.