Shot a lot of Sigs in my day, granted they aren't as numerous as the other folks around here, and I've had no problems. Only thing on them is cost, eight to nine hundred dollars new but one of the best fighting pistols around. Also look into Springfield, the XD45's I've shot have all been great performers with no issues. And remember, when gun people take reliability, it usually refers to 'in the field'. At home all these guns are going to be reliable once you've proven them at the range.
Big thing is price. How much do you have, or are willing to spend, on a handgun? That'll narrow your options for you real quick. Split, I'd say, into: Sig, FN, Kimber, HK between Springfield, Glock, Smith Wesson, Ruger. High end and utilitarian.
And there's what your familiar with and comfortable handling. Lots of stuff going on when using a Sig or a 1911, lots of room to make mistakes. On the other hand, those inexpensive polymer frames are fairly simple; point, pull trigger, take finger off trigger when done. If your not that comfortable a shooter that would be the route I'd recommend and have to good friends in the past.
My personal favorite to your actual question though is Sig. Good luck.