For those with a variety of calibers at their disposal, I'm positive the consensus for home defense is larger than a .380 caliber.
However, I carry my Kel-Tec P3AT most of the time, or my Walther PPK/S, in sunny, hot, humid, can't turn the damn AC off yet,..oh nevermind,...
Anyway, if a .380 was all I had for home defense, I darn sure would be making range trips, like several a month if possible, and keeping nothing but top shelf, fresh, premium JHP's in it. Snap caps, drawing techniques, spare mags, a PLAN, safe room, etc,...
Hard to do with ammo being scarce, but I would invest in Golden Sabre's, Speer Gold Dot, Cor-Bon DPX, type stuff for the home,
just like I do on the street.
Keep shooting until the threat has stopped, and be ready to reload and keep going.
And if this doesn't help, if you get a tax refund, buy a caliber that begins with the number .4 ......or at least .357...
.02 cents worth.