I have to question some of these self defense "rules" a bit. I hear at least 500 to 1,000 rounds for a "brake in", then at least 200 rounds of whatever factory self defense ammo you'll be carrying. With cheap .45 ACP hardball going for $20.00+ a box now, that equates to at least $400.00+. Now add in the 200 rounds of premium self defense ammo at around $22.00+ for 20, that is another $220.00+. Now you're up to a minimum of $620.00, or more than you paid for the Glock you're going to run it through.
Yes, if you handload you can carve off a big chunk of that, but most CCW owners don't handload. With the cost of the gun you're talking over $1,200.00 by the time you become harder to take down than Steve McQueen. That isn't much to quibble about with something that protects your life. But, with that said in today's economy few CCW holders are going to do it simply because they cannot afford it.
Everyone cringes when someone mentions FMJ roundnose hardball for self defense applications, but there are a lot of enemy soldiers that are in the cemetery because of exactly that. I think a better solution is to shoot as much cheap hardball as you can afford. When you do have a few extra bucks buy a box of the high priced stuff and run it through. If, over time, you find that you have run 80 or 100 rounds, (4 or 5 boxes), of premium ammo with no hangups, go ahead and use it. I base this on the fact most auto pistols will either run with a given brand or configuration of ammo, or they won't.
If they won't you'll see it with the first magazine full most of the time. "Sometimes" problems in guns are far more rare than they are in cars. If there still is doubt use hardball for carry. If you can shoot accurately it is going to have far more bearing on your survival than some super trick ammo will. A gun has to go bang to defend you. Everything else is speculative. Bill T.