Historically, I've carried a Blade-Tech IWB more than any other real holster for full size guns (Glock 23, mostly, since the mid 90's). That said, over the last several years, I've carried a J-frame IWB in a Belly Band more than anything else. This year, when I have carried a full size gun IWB, it has been most often with a Crossbreed. I was pretty surprised and how much I liked the Crossbreed (with the "combat cut), not the original so much.) If you are starting from scratch, I would say check out the CBH!
-RJP