Unlike FQ, I shoot pistols lefty, and rifles righty.. On those non ambi-semi autos, like the PPK/S, EAA, I adapt with my index finger for mag release, slide release, and left thumb, for safety engage/disengage. It does take practice.
With a semi, DO NOT pass the gun hand to hand, it's a time consuming habit. A fellow member told me that for something to develop into muscle memory, it must be done 70 times.
From a locked open slide,pistol in your left hand, (unloaded of course, or snap caps), drop the mag with your index finger, while bringing another empty mag up with your right hand, keep the muzzle pointed down range, turning it outward to ease reloading than bring the pistol back on target, and try to close the slide one or two ways.
Index finger, or right had racks (or 1/2 racks) to close.
Revolvers: Different animal. As a southpaw, this requires much more personal style and preference. I personally use speedloaders, but I have to swing open the cylinder, cradle the revolver in my left hand, middle and ring finger through the frame holding open the cylinder, point it up and away, slap the ejector rod with my right hand, (if needed), than muzzle pointed down, and bring the speedloader, to the cylinder reload. It's smoother than it sounds, but takes practice. ALOT, like 15min-1/2 hour a day with snap caps. But the revolver stays in the strong hand throughout.
Especially from holster. Even more with a snubby.

Most holster makers have LH Holsters, your local gun shop just may not carry more than one or two. Online resources, are very helpful.
Hope this helps. Since we Southpaws, are in our "Right Minds", generally we adapt with practice. I will recommend reading the "Natural Superiority Of The Left-Hander", by James T. deKay.
