I only use brand "B" I would laugh, having seen both brands being loaded from the same pump. But brand "B" was 2 or 3 cents more per gallon 
Having never owned a car( I don't have a license to drive one), but riding bikes most of my adult life, I can't comment on how various brands of gas would affect cars, but I have noticed differences in how various brands of gas would do in my bikes.
For the record: my bikes included a Yamaha XJ600F, Yamaha SRX 6, Honda XBR500/GB500TT, Honda CB750KZ, Honda CBX-1000, BMW R100RS (never should have sold that one

) and a Italjet Formula 125 scooter.
Most brands would bring similar results in MPG, but using for example Shell gas in my CBX, Yamaha's and BMW would result in a higher fuel consumption, where as Mobil gas would do the opposite. I realise that this is not a scientific study, but I think it might be smart just to experiment with various brands and keeping record of various fuel consumption figures.
Ocin.