Go with the glock 19!!! Look, any glock will do what is supposed to.
1 Shoot 4" at 15-20 yds
2 Go bang EVERY time you pull the trigger no matter what you load it with
Yes I've drunk the Kool-aid, but it doesnt make it less true.The glock is a weapon. Not a target pistol, not a hunting firearm, not a work of art, a weapon. Nothng more, nothing less. No BS, no half-cock or safties or anything else. Just point and click.
That leaves you with the choice of .40 vs 9 mm. Frankly they are both good rounds, and a zillion police and sheriffs departments agree. I would just say that the .40, a compromise between the the 9mm and .45, is not that much better than the 9. It has fewer choices of mags than will fit a 19, and is a lot more expensive and harder to find than either 9mm or .45, and has fewer commercial SD rounds available. (Do not use reloads in a glock). As far as more exotic loads like the .357 sig, me, I like to keep it simple. If I can't find ammo for it at wally world, I don't want to own it.Because a hand gun for sef defense is all about trade offs. One of those (to me at least) is the price and availability of ammo and mags. Just my .02.
FQ13