As a lefty who usually has to adapt to a righty world, I had Brownell's ambi safety installed by a gunsmith for my S&W 1911.

It was less expensive than a "left" handed 1911, and I have just gotten used to the mag release with my left trigger finger.
However, the ambi safety IS great. If carried cocked and locked, the ambi is a must for a lefty.
Other pistols I have are also ambi, the M+P can be made totally left handed, and the others have controls on both sides, except for a mag release.
My revolvers, well you just get used to the cylinder swinging outboard, and with practice, "speedloaders" help immensely. Snap caps, and practice, practice, practice. I'm not Jerry Miculek fast, (who is?), but pretty darn quick with my revolvers.
I recommend the book "Natural Superiority of the Left Hander" , by James T. deKay.
