The Ruger catalog has a .480 round, I guess to get a mine is bigger than yours (.460) type of contest.
Article said similiar to a 44 Magnum recoil. How big is big for a handgun?
Is it marketing hype? I can't imagine the ballistics are that much different, but as far as hunting, here in NC you cannot go deer hunting with a .22 WMR. Even if a head shot would drop it like a bad habit.