In my extensive research (The gun shop's rental counter and shooting range) I've shot a couple of hundred rounds through 9mm, 40sw, and .45 acp in Glock, HK USP, Sig 220 Carry and 226, Springfield XD and Wilson Combat. The guy at the rental counter really teased me with the Wilson...no way I'm affording that...so that's out of the picture on price alone. Glocks...good guns but I just can't get my stubby trigger finger around that trigger comfortably. HK USP were fine but I didn't like the mag release. I had to shift the gun around too much to get to it. Sigs were really good, accurate, comfortable for my hand, trigger and mag release easy to reach, came on target to my eye really well. The XD was really good; Very controllable in .45 and the trigger was really nice, easy to reach, as well as the mag release.
Right now it's between the Sig P220 Carry or the Springfield XD in .45acp.